Common Symptoms

Symptoms will depend on the type of blood cells that are affected.

A drop in the number of normal white blood cells makes it harder for the body to fight infection and may lead to:

• Persistent fever that is not specific to another condition
• Flu-like symptoms
• Night sweats
• Minor cuts that heal slowly—the area around the cut may become red and swollen

A drop in the number of normal red blood cells is called anemia, which decreases the amount of oxygen reaching the body's tissues. Symptoms of anemia may include:

• Weakness and fatigue
• Pale skin
• Headache

A drop in the number of normal platelet cells makes it harder for blood to clot properly. Without clotting, even small injuries can lead to severe bleeding. Symptoms may include:

• Bleeding or bruising easily
• Nosebleeds
• Bleeding gums
• Tiny red spots under the skin
• Heavy menstruation

Advanced Symptoms

Later stages of leukemia may cause:

• Swollen, tender lymph nodes
• Swelling of the liver or spleen
• Puffy gums
• Rash
• Decreased appetite and unintended weight loss
• Bone or joint pain
• Difficulty breathing
• Swelling of the testicles
• Nervous system problems, including:
  • Headaches
  • Nausea
  • Loss of muscle control
  • Seizures