Definition

Inflammatory bowel disease (IBD) is swelling and irritation of the intestines. Two forms of IBD are:

• Crohn disease
• Ulcerative colitis

IBD is a lifelong illness.

Causes    TOP

The exact cause of IBD is not known. Some believe IBD may be the result of:

• Inherited genetics—may be a family history of IBD
• Reaction to a virus or bacteria that damages the colon and rectum
• Compromised immune system or infection that affects the immune system

Risk Factors    TOP

IBD is more common in people who are Caucasian or of northern European or Jewish ancestry.

The following factors increase your chance of developing IBD:

• Having a family member with IBD
• Having problems with the immune system

Symptoms    TOP

Symptoms may be constant or occur during flare-ups. Symptoms depend on the type of IBD, but common symptoms may include:

• Abdominal pain and cramping
• Diarrhea
• Weight loss and loss of appetite
• Bleeding from the intestines
• Ulcers in the intestines
• Inflammation of the rectum
• Draining around the rectum
• Bloating or feeling of fullness
• Gas
• Bloody diarrhea
• Abdominal sounds such as gurgling
• Nausea and vomiting
• Joint pain

Diagnosis    TOP

You will be asked about your symptoms and medical history. A physical exam will be done.

Images of your bodily structures may be needed. This can be done with:

• Upper GI endoscopy
• Colonoscopy
• Barium enema
• X-ray
• Capsule endoscopy

Your bodily fluids and waste products may be tested. This can be done with:

• Blood tests
• Stool culture

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Treatment    TOP

There is no cure for IBD but treatments can help control symptoms. Talk with your doctor about the best treatment plan for you. Treatment options include:

Prevention    TOP

There are no current guidelines to prevent IBD because the cause is unknown.