(Fish Scale Disease; Xeroderma)
by Cynthia M. Johnson, MA
Ichthyosis is a group of skin disorders that cause dryness and scaling. There are two main types:
The inherited type is caused by a genetic defect that is passed from parent to child or that occurs on its own.
The acquired type may be caused by health problems, such as:
Things that may raise the risk of this problem are:
It can affect any part of the body. It is common on the legs, arms, and trunk. Symptoms can be mild to severe and include:
The doctor will ask about your symptoms and health history. You may also be asked about your family history. A physical exam will be done. It will focus on the skin.
Blood tests may be done to look for signs of the gene linked to this health problem.
There is no cure. The goal of treatment is to manage symptoms. Any underlying cause will also need to be treated.
Treatment may include:
There are no current guidelines to prevent this health problem.
Foundation for Ichthyosis & Related Skin Types
The National Registry for Ichthyosis and Related Disorders
Canadian Dermatology Association
Ichthyosis. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/ichthyosis. Accessed March 24, 2021.
Ichthyosis. DermNet NZ website. Available at: https://www.dermnetnz.org/topics/ichthyosis. Accessed March 24, 2021.
Newly diagnosed? Foundation for Ichthyosis & Related Skin Types website. Available at:
...(Click grey area to select URL)
Accessed March 24, 2021.
Schmuth M, Martinz V, et al. Inherited ichthyoses/generalized Mendelian disorders of cornification. Eur J Hum Genet. 2013 Feb;21(2):123-133.
Last reviewed December 2020 by EBSCO Medical Review Board Daniel A. Ostrovsky, MD
Last Updated: 03/24/2021
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