Diagnosis and Prognosis of Uterine (Endometrial) Cancer
by Cynthia M. Johnson, MA
The doctor will ask about your symptoms and health history. You will also be asked about your family health history. A physical and pelvic exam will be done. This may be enough to suspect uterine cancer. These tests will be done to confirm the diagnosis:
Staging of Uterine Cancer
Tests will help to identify the stage of cancer. Staging looks at the cancer and whether it has spread. It will look at whether lymph nodes are involved. This will help guide treatment.
A laparotomy will be done through an incision in the abdomen. The pelvis will be examined for signs of cancer. Cancerous tumors, tissue, or organs may be taken out.
Tests that may be done are:
Stages of Uterine Cancer
Uterine cancer is staged from I-IV (1-4):
Grading of Uterine Cancer
Uterine cancer can be graded by how cells looks under a microscope. It is grouped as low or high risk.
Prognosis is an estimate of the course and outcome of the cancer. It is often given as a percentage of the people who are expected to survive over 5 or 10 years.
On average, the 5-year survival rate for uterine cancer is about 81%. Individual rates depend on the stage of the cancer at the time of diagnosis. Uterine cancer found in the earliest stages (stage IA [1A]) offer the best chance for a cure. Survival rates can be as high as 90%. Survival rates get lower as cancer stages increase. Women with stage IV (4) uterine cancer have a survival rate of about 15%.
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Endometrial cancer. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/endometrial-cancer. Updated October 21, 2019. Accessed February 26, 2020.
Endometrial cancer. Merck Manual Professional Version website. Available at:
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Updated February 2019. Accessed February 26, 2020.
Fernandez C, Levine E, et al. Predictive value of three-dimensional transvaginal sonography for staging of endometrial neoplasia. Journal of Diagnostic Medical Sonography. 2018;34(6):496-500.
Renaud MC, Le T, et al. Epidemiology and investigations for suspected endometrial cancer. J Obstet Gynaecol Can 2018 Sep;40(9):e703.
Last reviewed November 2019 by EBSCO Medical Review Board Elliot M. Levine, MD, FACOG
Last Updated: 1/26/2021
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