Preventing Liver Disease

Image for liver disease in womenYour liver performs many vital jobs. Among other things, it removes toxins from your blood and stores vitamins, minerals, and fuel necessary to survive. Unfortunately, the liver is vulnerable to damage. Heres's what you should know to keep your liver healthy and prevent disease.

What Your Liver Does

Your liver is a large and complex organ. It is responsible for breaking down and eliminating naturally occurring toxins as well as many types of medications. It also acts as a chemical factory, producing bile (necessary for digestion), clotting factors, other proteins in the blood, as well as cholesterol and various forms of fats. The other major function of the liver is to store and release carbohydrates.

Just performing its duties makes your liver vulnerable to injury. For instance, deactivating potentially harmful drugs and medications is a hazardous job. Drug breakdown can damage liver cells and result in acute or chronic liver disease. Preventable factors that may damage your liver include alcohol and drug abuse, medications, infections, and certain health conditions. The most common causes of liver disease are:

Types of Damage That Occur

Sometimes liver damage is acute and potentially reversible. Other times it’s chronic and irreversible. Common signs of acute liver disease include jaundice (yellowing of the skin and eyes), nausea and vomiting, fatigue, and abdominal pain plus abnormal liver blood tests.

When damage becomes progressive and irreversible, it may lead to chronic liver disease. Permanent loss of liver function can result from a complication called cirrhosis, or scarring of the liver. In severe cases, a liver transplant may be required to sustain life.

Other problems that are associated with chronic liver disease include fluid build-up in the abdomen (ascites), trouble thinking clearly ( encephalopathy), gastrointestinal bleeding, bleeding disorders, and a greatly increased risk of liver cancer.

Disease Prevention

Since chronic liver disease cannot be cured, prevention is key. Here are some tips to help you reduce your risk of developing liver disease for each of the most common causes.

Viral Hepatitis

Several contagious viruses can cause of inflammation of the liver (hepatitis):

  • Hepatitis A and E are spread through contaminated food and water or by person-to-person contact. The infection usually does not progress to chronic hepatitis. Preventive measures include:
    • Get the hepatitis A vaccine if you are at high risk for hepatitis A.
    • Wash your hands with soap and water. This is very important after using the bathroom or changing a diaper.
    • Wash your hands with soap and water before eating or preparing food.
    • Avoid using household utensils that a person with hepatitis A may touch. Make sure all household utensils are carefully cleaned.
    • Avoid sexual contact with a person with hepatitis A.
    • If you travel to a high risk region, take the following precautions:
      • Drink bottled water.
      • Avoid ice chips.
      • Wash fruits well.
      • Eat well-cooked food.
      • At least one month before travel, ask your doctor if you need a hepatitis A vaccine or immune globulin shot.
  • Hepatitis B, C, and D are transmitted through exposure to infected blood, sexual contact, childbirth (mother to child), or affected family members. The infection can progress to chronic hepatitis. Preventive measures include:
    • Use condoms consistently and correctly or avoid sexual contact.
    • Limit your number of sexual partners. Aim for mutually monogamous relationships.
    • Do not inject drugs. If you use IV drugs, get treatment to help you stop.
    • Never share needles or syringes.
    • Do not share personal items that might have blood on them, such as:
      • Razors
      • Toothbrushes
      • Manicuring tools
      • Pierced earrings
    • Get vaccinated against hepatitis B if you are at high risk for contracting hepatitis B
    • If you get a tattoo or body piercing, make sure the artist or piercer properly sterilizes the equipment. You might get infected if the tools have someone else's blood on them.
    • If you are a healthcare or public safety worker, always follow routine barrier precautions and safely handle needles and other sharp instruments.
    • Wear gloves when touching or cleaning up body fluids on items such as:
      • Bandages
      • Band-aids
      • Tampons
      • Linens
    • Cover open cuts or wounds.
    • If you are pregnant, have a blood test for hepatitis B.

Heavy Alcohol Consumption

Heavy alcohol consumption can result in damage to the liver cells and eventually cirrhosis. Preventive measures include:

  • Drink in moderation—Moderation is a maximum of 1 drink per day for women and 2 drinks per day for men.
  • If you already have liver problems, don’t drink at all.


Excess weight can cause a potentially harmful buildup of fat in the liver. Fatty liver disease usually does not cause symptoms. It may appear as abnormal liver blood tests that can eventually progress to cirrhosis. If you are overweight, work to gradually lose excess weight through diet and exercise.


Hemochromatosis is a relatively common hereditary disorder that causes excessive iron storage in the liver. This can eventually lead to impaired liver function and cirrhosis. Blood tests (for iron and iron-carrying protein) to detect the disease and phlebotomy (bloodletting) to treat the disease can prevent these complications, especially when diagnosed and treated early.

Medications and Supplements

Many drugs can act as toxins to your liver, including acetaminophen (when taken in excess), anesthetics, seizure medications, antibiotics used for tuberculosis, and some cholesterol reducers. Certain herbs and supplements can be toxic to the liver as well, including very high doses of vitamin A or niacin, comfrey, germander, coltsfoot, and sassafras.

Always talk to your doctor about potential side effects before taking any supplements or medications. Ask if you should have liver tests due to the medications or supplements you are taking.

Detection of Disease

If liver disease does occur, the best time to detect it is early. Inform your doctor of any factors you have that may increase your risk for liver disease. Your doctor can monitor your liver function with blood tests and order further testing if necessary. If abnormalities persist, make sure your doctor follows up on them and adequately explains the cause or refers you to a gastroenterologist.


American Liver Foundation
National Institute of Diabetes and Digestive and Kidney Diseases


The Canadian Association of Gastroenterology
Canadian Liver Foundation


Alcoholic liver disease. EBSCO DynaMed Plus website. Available at: Updated June 14, 2017. Accessed October 12, 2017.
Cirrhosis of the liver. EBSCO DynaMed Plus website. Available at: Updated May 31, 2017. Accessed October 12, 2017.
Nonalcoholic fatty liver disease (NAFLD). EBSCO DynaMed Plus website. Available at: https://www.dyname.... Updated May 19, 2016. Accessed October 12, 2017.
Resnick RH, Chopra S. Nonalcoholic steatohepatitis: a common hepatic disorder. Family Practice Recertification. 2002;24:43-50.
Riley TR, Bhatti AM. Preventive strategies in chronic liver disease: Part I. Alcohol, vaccines, toxic medications and supplements, diet and exercise. Am Fam Physician. 2001;64(9):1555-1560.
Riley TR, Bhatti AM. Preventive strategies in chronic liver disease: Part II. Cirrhosis. Am Fam Physician. 2001;64(10):1735-1740.
Symptoms of liver disease. US Department of Veterans Affairs website. Available at:
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Accessed October 12, 2017.
Last reviewed October 2017 by EBSCO Medical Review Board Michael Woods, MD, FAAP
Last Updated: 12/1/2015

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