Lobular Carcinoma in Situ
by Amy Scholten, MPH
Lobular carcinoma in situ (LCIS) is when there are abnormal cells in the lobules of the breast. The lobules are the part of the breast that produces milk. LCIS is not cancer. However, it can raise the risk of future breast cancer.
It is not clear what causes LCIS. It is likely due to a change in a gene.
LCIS is more common in premenopausal women between 40 to 50 years old.
LCIS does not have symptoms.
LCIS does not appear on imaging tests. It cannot be felt during a breast exam. It is usually found during a biopsy of other nearby breast tissue.
LCIS does not require treatment.
The doctor will monitor the breast for changes with:
The risk of breast cancer may be reduced by:
American Cancer Society
National Cancer Institute
Canadian Cancer Society
LCIS—lobular carcinoma in situ. Breast Cancer website. Available at:
...(Click grey area to select URL)
Accessed March 19, 2021.
Lobular carcinoma in situ. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/lobular-carcinoma-in-situ. Accessed March 19, 2021.
Lobular carcinoma in situ (LCIS). American Cancer Society website. Available at: https://www.cancer.org/cancer/breast-cancer/non-cancerous-breast-conditions/lobular-carcinoma-in-situ.html. Accessed March 19, 2021.
Wen HY, Brogi E. Lobular carcinoma in situ. Surg Pathol Clin. 2018;11(1):123-145.
Last reviewed January 2021 by EBSCO Medical Review Board Mohei Abouzied, MD, FACP
Last Updated: 3/19/2021
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at email@example.com. Our Health Library Support team will respond to your email request within 2 business days.
All rights reserved.