Symptoms of Peptic Ulcer Disease
by Cynthia M. Johnson, MA
Some people do not have symptoms. In others, symptoms may come and go. Problems may be:
Ulcers can cause bleeding. It is rare but heavier bleeding can cause:
National Institute for Health and Clinical Excellence (NICE). Dyspepsia and gastro-esophageal reflux disease: Investigation and management of dyspepsia, symptoms suggestive of gastro-esophageal reflux disease, or both. NICE 2014 Sep:CG184.
Peptic ulcer disease. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/peptic-ulcer-disease. Updated April 2, 2018. Accessed February 3, 2020.
Peptic ulcer disease. Merck Manual Professional Version website. Available at:
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Updated January 2020. Accessed February 3, 2020.
Peptic ulcers (stomach ulcers). National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: https://www.niddk.nih.gov/health-information/digestive-diseases/peptic-ulcers-stomach-ulcers/all-content. Updated November 2014. Accessed February 3, 2020.
Last reviewed November 2019 by EBSCO Medical Review Board Daniel A. Ostrovsky, MD
Last Updated: 2/9/2021
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