Alpha-adrenergic Blocking Agents
Alpha-adrenergic blocking agents (or alpha-1 blockers) help smooth muscle relax. This can help to open blood vessels and improve blood flow. It can be part of a treatment plan for high blood pressure. It may also be used to ease urinary retention with BPH (benign prostatic hyperplasia).
Drugs in this category include:
Possible Harmful Interaction
Quercetin may be used to manage prostate issues. Tamsulosin can be used to help men with BPH who have urinary flow problems. Since they both have similar effect it may not be wise to combine them. An animal study suggests that combining the two may exaggerate the effect of the drug.4
1. Terazosin. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T233446/Terazosin. Updated March 6, 2018. Accessed April 11, 2018.
2. White LM, Gardner SF, Gurley BJ, Marx MA, Wang PL, Estes M. Pharmacokinetics and cardiovascular effects of ma-huang (Ephedra sinica) in normotensive adults. J Clin Pharmacol. 1997;37(2):116-122.
3. Murburg MM, Villacres EC, Ko GN, Veith RC. Effects of yohimbine on human sympathetic nervous system function. J Clin Endocrinol Metab. 1991;73(4):861-865.
4. Vrolijk MF, Haenen GR, Opperhuizen A , et al. The supplement-drug interaction of quercetin with tamsulosin on vasorelaxation. Eur J Pharmacol. 2015 Jan 5;746:132-7.
Last reviewed September 2018 by EBSCO CAM Review Board
Last Updated: 9/5/2018
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at email@example.com. Our Health Library Support team will respond to your email request within 2 business days.