Medical Condition Library

Information Centers

Wellness Centers

Helpful Resources

Hydralazine

Home | Health Information Center | Natural & Alternative Treatments | Drug Interactions | Article

Vitamin B6 - Supplementation Likely Helpful

Coenzyme Q10 (CoQ10) - Supplementation Possibly Helpful

Coleus forskohlii - Theoretical Interaction

En Español

Hydralazine causes dilation of the walls of blood vessels and is sometimes used to treat hypertension.

Vitamin B6

Supplementation Likely Helpful

Hydralazine is known to deplete the blood of vitamin B 6. Taking B 6 supplements may prevent or reverse side effects of the medication.1,2

Coenzyme Q10 (CoQ10)

Supplementation Possibly Helpful

There is some evidence that hydralazine might impair the body's ability to manufacture the substance coenzyme Q 10 (CoQ 10).3 This suggests (but definitely does not prove) that taking CoQ 10 supplements may produce a beneficial effect.

Coleus forskohlii

Theoretical Interaction

The herb Coleus forskohlii relaxes blood vessels and might have unpredictable effects if combined with hydralazine.

References►

1. Shils M, et al. (eds.). Modern nutrition in health and disease, 9th ed. Baltimore: Williams and Wilkins, 1999: 1634.

2. Goodman L and Gilman A. The pharmacological basis of therapeutics, 9th ed. Hardman J, et al (eds.). New York: McGraw-Hill, 1996: 1562.

3. Kishi H, et al. Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q 10 -enzymes by clinically used anti-hypertensive drugs. Res Commun ChemPathol Pharmacol 12(3): 533–40, 1975.

Last reviewed December 2015 by EBSCO CAM Review Board
Last Updated: 12/15/2015

EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.

To send comments or feedback to our Editorial Team regarding the content please email us at healthlibrarysupport@ebsco.com. Our Health Library Support team will respond to your email request within 2 business days.