Reducing Your Risk of Uterine (Endometrial) Cancer

A risk factor is something that increases your chances of developing cancer. Some risk factors cannot be modified such as your age or genes. Others may be reduced or avoided.

  • Manage abnormal endometrial cells —Endometrial intraepithelial neoplasia (EIN) may appear years before uterine cancer. Treatment may help to prevent them from turning into cancer.
  • Lose excess weight or maintain a healthy weight —Higher estrogen levels are associated with increased weight. Talk to your doctor about how to lose weight safely. Eating a well-balanced, nutritious diet will help with maintaining weight within a normal range. It will also help reduce the chance of diabetes, which in turn, lowers uterine cancer risk.
  • Exercise regularly —Physical activity is associated with many benefits, including weight control, and reducing blood pressure and the risk of uterine cancer. Aim for at least 30 minutes a day on most days of the week. This can be as easy as taking a brisk walk. If you are not used to regular exercise, talk to your doctor before starting any exercise program.
  • Do not smoke. If you do smoke, look for ways to help you stop. There are many tools now available.

Other steps that may reduce the risk include:

  • Breastfeeding —If you have a baby, breastfeeding will also reduce the risk of uterine cancer. This is especially true for women who breastfeed for a longer period of time.
  • Birth control—may lower your risk. However, it should not be used solely to reduce risk of uterine cancer.


Can endometrial cancer be prevented? American Cancer Society website. Available at: Updated February 29, 2016. Accessed December 6, 2017.
Endometrial cancer. EBSCO DynaMed Plus website. Available at: Updated May 24, 2017. Accessed December 6, 2017.
Endometrial cancer. The American College of Obstetricians and Gynecologists website. Available at: Updated June 2016. Accessed December 6, 2017.
Endometrial cancer prevention. National Cancer Institute website. Available at: Updated April 7, 2017. Accessed December 6, 2017.
Last reviewed December 2017 by EBSCO Medical Review Board Mohei Abouzied, MD, FACP
Last Updated: 12/6/2017

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