by Michael Jubinville, MPH
Neuroblastoma is a rare cancer. It usually starts in nerve tissue near the adrenal glands. They are found just above the kidneys. However, some may start and grow in other parts of the body.
It may be found when your child is an baby. In some, the tumor may start before birth.
Cancer is when cells in the body split without control or order. These cells go on to form a growth or tumor. The term cancer refers to harmful growths. These growths attack nearby tissues. They also spread to other parts of the body. It’s not clear exactly what causes these problems. It’s likely a mix of genes and the environment.
Neuroblastoma is mainly found in children under 5 years old. It’s also more common in males. Your child’s chances are also higher for:
Symptoms will depend on the where the tumor is and if it’s spread. Some include:
Problems may be caused by a hormone imbalance caused by the tumor. These will depend on the hormone.
The doctor will ask about your child’s symptoms and health history. Your answers and a physical exam may point to a neuroblastoma.
Your child may also have:
The test results will help find if the tumor is localized or if it’s spread. This helps with making a treatment plan.
Some neuroblastomas go away on their own. Your child’s doctor may want a period of time to observe for any changes.
If needed, methods to treat neuroblastoma may be combined.
Small tumors may be removed with surgery. In low risk cases, this may offer a cure.
Chemotherapy and Radiation Therapy
Chemotherapy is the use of drugs to kill cancer cells. The drugs enter the bloodstream and travel through the body.
With radiation therapy, radiation is aimed at the tumor to kill the cancer cells. This may be used if the cancer has spread.
Bone Marrow Transplantation
Bone marrow is removed, treated, and frozen. High dose chemotherapy or radiation kills any leftover cancer cells. It’s replaced by your child’s own bone marrow or from a healthy donor. It’s put back in the body through an IV.
There is no way to prevent neuroblastomas since the cause is unknown.
American Cancer Society
The Neuroblastoma Children’s Cancer Society
Canadian Cancer Society
Childhood Cancer Canada
General information about neuroblastoma. National Cancer Institute website. Available at: https://www.cancer.gov/types/neuroblastoma/patient/neuroblastoma-treatment-pdq. Updated July 6, 2018. Accessed July 31, 2018.
Neuroblastoma. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T115227/Neuroblastoma . Updated February 15, 2018. Accessed July 31, 2018.
Neuroblastoma. Kids Health—Nemours Foundation website. Available at: https://kidshealth.org/en/parents/neuroblastoma.html. Updated January 2017. Accessed July 31, 2018.
Last reviewed May 2018 by EBSCO Medical Review Board Mohei Abouzied, MD, FACP
Last Updated: 7/31/2018
EBSCO Information Services is fully accredited by URAC. URAC is an independent, nonprofit health care accrediting organization dedicated to promoting health care quality through accreditation, certification and commendation.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
To send comments or feedback to our Editorial Team regarding the content please email us at firstname.lastname@example.org. Our Health Library Support team will respond to your email request within 2 business days.