Polymyalgia Rheumatica
Condition
(PMR)
Definition
Polymyalgia rheumatica (PMR) is a disease that causes inflammation throughout the body. It results in muscle pain and stiffness.
Causes
The cause of PMR is unknown. Genes and things in the environment may play a role.
Risk Factors
PMR is most common in people over 50 years of age. It is more common in women and people of European descent.
Symptoms
Symptoms of PMR may include:
- Muscle pain and stiffness in the hip, shoulder, or neck
- Pain that spreads to the elbows or knees
- Low energy
- Morning stiffness lasting longer than 30 minutes
- Weight loss without a known cause
- Fever
Diagnosis
The doctor will ask about symptoms and past health. A physical exam will be done. PMR will be suspected if symptoms are there for more than 2 weeks.
A blood test may be done to rule out other causes.
Treatment
Treatment often leads to quick relief. Steps may include:
- Corticosteroids—may be used for up to 2 years at low doses
- Anti-inflammatory medicine
- Interleukin-6 (IL-6) antagonists when corticosteroids cannot be taken or are not helpful
Long term steroids can cause bone loss. Supplements may be given to stop bone loss.
Prevention
PMR can not be prevented.
American College of Rheumatology
Arthritis Foundation
CANADIAN RESOURCES:
Health Canada
The Arthritis Society
American College of Rheumatology
Arthritis Foundation
CANADIAN RESOURCES:
Health Canada
The Arthritis Society
References
- Polymyalgia rheumatica. American College of Rheumatology website. Available at: https://rheumatology.org/patients/polymyalgia-rheumatica.
- Polymyalgia rheumatica (PMR). EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/polymyalgia-rheumatica-pmr.
- Polymyalgia rheumatica and giant cell arteritis. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: https://www.niams.nih.gov/health-topics/polymyalgia-rheumatica-giant-cell-arteritis.
- 3/24/2023 EBSCO DynaMed Systematic Literature Surveillance https://www.dynamed.com/condition/polymyalgia-rheumatica-pmr: Kevzara label. FDA website. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/761037s013lbl.pdf.
Contributors
- April Scott, NP
(C) Copyright 2023 EBSCO Information Services
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