(Androblastoma; Sertoli-Leydig Cell Tumor of the Ovary)
An arrhenoblastoma is a rare type of ovarian tumor that is often benign (not cancerous). The tumor cells release a male sex hormone called testosterone.
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The cause of arrhenoblastoma is not known.
Arrhenoblastoma can happen in girls and women of all age groups. However, it is more common in women between 20 and 30 years of age.
In many women, irregular or absent menstrual periods are the only symptom of arrhenoblastoma.
In others, the male hormones released by the tumor may cause:
The doctor will ask about your symptoms and health history. A physical exam will be done.
Blood tests will be done to check hormone levels.
Images may be taken of the pelvis. This can be done with ultrasound .
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Surgery will be done to remove the tumor. If cancer has been found, it may also be treated with:
There are no known guidelines to prevent arrhenoblastoma.
- Ovarian cancer. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/ovarian-cancer.
- Sertoli-leydig cell tumors. Genetic and Rare Diseases Information Center—National Institutes of Health website. Available at: https://rarediseases.info.nih.gov/diseases/9967/sertoli-leydig-cell-tumors.
- Types of ovarian tumors. Johns Hopkins Medicine Pathology website. Available at: https://pathology.jhu.edu/ovarian-cancer/types-of-tumors.
- Beverly Siegal, MD, FACOG
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