Encephalitis
Condition
Definition
Encephalitis is swelling of the brain.
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Causes
Encephalitis can often be caused by an infection. Some common ones are:
- Herpes simplex virus (HSV)
- The varicella zoster virus, which causes chickenpox and shingles
- Measles, Mumps, and rubella
- Viruses carried by mosquitoes, such as West Nile or Eastern equine encephalitis
It can also be caused by a problem with the immune system, such as a tumor or having an infection in the body outside of the central nervous system.
Risk Factors
Some things that may raise the risk of encephalitis are:
- Spending time in places where viruses carried by mosquitoes or ticks are common
- Not getting vaccinated for diseases that can cause encephalitis
- Having a weakened immune system
Symptoms
A person with encephalitis may have:
- Nausea and vomiting
- Diarrhea or belly pain
- Fever
- Stiff neck or headache
- Sleepiness
- Loss of feeling or numbness in the body
- Confusion or personality changes
- Seizures
Diagnosis
The doctor will ask about symptoms and past health. A physical exam will be done.
Blood tests will be done to look for signs of infection. A lumbar puncture may be done to test the fluid around the brain and spine.
Pictures may be taken of the brain to look for changes. This can be done with:
Treatment
The underlying cause of the encephalitis will need to be treated. A team of specialists may be needed.
Medicines may be given, such as:
- Antiviral drugs to make the illness last a shorter time
- Steroids to ease swelling in the brain
- Medicines to ease pressure in the head
- Anti-seizure medicine to prevent and treat seizures
If a virus cannot be treated, then the goal may be to manage symptoms until the virus has passed on its own.
Prevention
Encephalitis may be prevented by:
- Staying up to date with vaccinations
- Taking steps to avoid mosquito and tick bites, especially in high risk areas.
Encephalitis Society
National Institute of Neurological Disorders and Stroke
CANADIAN RESOURCES:
Canadian Neurological Sciences Federation
Health Canada
Encephalitis Society
National Institute of Neurological Disorders and Stroke
CANADIAN RESOURCES:
Canadian Neurological Sciences Federation
Health Canada
References
- Eastern equine encephalitis. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/eastern-equine-encephalitis.
- Herpes simplex encephalitis. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/herpes-simplex-encephalitis.
- Meningitis and encephalitis information page. National Institute of Neurologic Disorders and Stroke website. Available at: https://www.ninds.nih.gov/Disorders/All-Disorders/Meningitis-and-Encephalitis-Information-Page.
- Grebenciucova E, Collins J, et al. Youmans Textbook of Neurological Surgery, 8th Edition. Neurologic manifestations of human immunodeficiency virus infection and acquired immunodeficiency syndrome. Elsevier. 2022.
- West Nile virus infection. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/west-nile-virus-infection.
Contributors
- David L. Horn, MD, FACP
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