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Lobular Carcinoma in Situ

Authors:
  • Amy Scholten, MPH
Publication Type:

Condition

Lobular Carcinoma in Situ

(LCIS)

Definition

Lobular carcinoma in situ (LCIS) is when there are abnormal cells in the lobules of the breast. The lobules are the part of the breast that produces milk. LCIS is not cancer. However, it can raise the risk of future breast cancer.

Causes

It is not clear what causes LCIS. It is likely due to a change in a gene.

Risk Factors

LCIS is more common in premenopausal women between 40 to 50 years old.

Symptoms

LCIS does not have symptoms.

Diagnosis

LCIS does not appear on imaging tests. It cannot be felt during a breast exam. It is usually found during a biopsy of other nearby breast tissue.

Treatment

LCIS does not require treatment.

The doctor will monitor the breast for changes with:

  • A physical and breast exam every 6 to 12 months
  • A yearly mammogram

Prevention

The risk of breast cancer may be reduced by:

  • Reaching and keeping a healthy weight
  • Regular physical activity
  • Eating a healthful diet
  • Avoiding alcohol or—or limiting it to 1 drink or less per day
RESOURCES:

CANADIAN RESOURCES:

CANADIAN RESOURCES:

References

  • LCIS—lobular carcinoma in situ and atypical lobular hyperplasia. Breast Cancer website. Available at: https://www.breastcancer.org/benign-breast-conditions/lobular-carcinoma-in-situ-atypical-lobular-hyperplasia.
  • Lobular carcinoma in situ. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/lobular-carcinoma-in-situ.
  • Lobular carcinoma in situ (LCIS). American Cancer Society website. Available at: https://www.cancer.org/cancer/breast-cancer/non-cancerous-breast-conditions/lobular-carcinoma-in-situ.html.
  • Wen HY, Brogi E. Lobular carcinoma in situ. Surg Pathol Clin. 2018;11(1):123-145.

Contributors

  • Mohei Abouzied, MD, FACP
Last Updated:
2022-09-01

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This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.