Actinic keratosis (AK) is a rough, scaly, or crusted patch of skin. It often happens from being in the sun. It is not cancer, but it can change to squamous cell skin cancer.
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AK is caused by damage from the sun or indoor tanning machines.
AK is more common in older adults. It is also more common in men. Other things that may raise the risk are:
- Fair skin color
- Living in sunny places
- Having a weak immune system, such as from an organ transplant
- Having xeroderma pigmentosum—a rare genetic disorder that causes increased sensitivity to the sun's rays
- Having chronic lymphocytic leukemia—a cancer of the blood and bone marrow
A person may have a rough, scaly, or crusted patch of skin.
You will be asked about your symptoms and health history. A physical exam will be done.
A biopsy may be done. The skin will be checked for cancer in a lab.
Treatment depends on whether the AK is mild or severe. A mild AK may be watched to check for changes over time. A severe AK may be treated to lower the risk of skin cancer. This may be done with:
- Medicine put on the skin over time to remove the AK
- Photodynamic therapy (may be done with laser treatment)
To lower the chance of getting AK:
- Limit time in the sun.
- Wear clothing to cover skin that is exposed to the sun.
- Do not use indoor tanning machines.
- Use sunscreen with an SPF of at least 30.
- Actinic keratosis. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/actinic-keratosis. Accessed April 28, 2022.
- Actinic keratosis. The Skin Cancer Foundation website. Available at: http://www.skincancer.org/skin-cancer-information/actinic-keratosis. Accessed April 28, 2022.
- de Berker D., McGregor J.M., et al. British Association of Dermatologists' guidelines for the care of patients with actinic keratosis. Br J Dermatol. 2017; 176 (1): 20-43.
- Sunscreen FAQs. American Academy of Dermatology website. Available at: https://www.aad.org/media-resources/stats-and-facts/prevention-and-care/sunscreen-faqs. Accessed April 28, 2022.
- James P. Cornell, MD
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