Risk Factors for Infertility in Women
Condition InDepth
A risk factor is something that raises the chances of getting a health problem. A person can become infertile with or without the ones listed below. The chances of becoming infertile are greater in people who have many.
Infertility is more common in those who are 35 years or older. This is when a woman has fewer eggs that can be fertilized.
Other things that can raise the risk are:
Health Problems
Many health problems can raise the risk of infertility.
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Problems That Impact Ovarian Function
These health problems can make it hard for the ovaries to work as they should:
- Polycystic ovary syndrome
- Poor thyroid function
- Pituitary tumors
- A history of problems with the immune system
Problems That May Harm or Block Fallopian Tubes
These health problems may make it hard for the fallopian tubes to work as they should:
- Endometriosis —Uterine tissue on other pelvic structures
- Pelvic inflammatory disease or previous pelvic surgery—can cause scarring
- History of ectopic pregnancy —A fertilized egg that grows in the tube can cause it to burst and may lead to scarring
Problems That May Harm the Uterus or Cervix
These health problems may make it hard for the uterus or cervix to work as they should:
- Structural problems
- Uterine polyps
- Uterine fibroids
Medications
Certain medicines can raise the risk of infertility, such as:
- Chemotherapy drugs
- Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen
- Prior use of contraceptive methods, such as an intrauterine device
Let your doctor know if you are taking any of these medicines. Talk about if you need to make changes.
Smoking, Drugs, and Alcohol Use
Tobacco use may lower fertility. Using marijuana or illegal drugs like cocaine can also raise the risk.
Excess alcohol can cause problems with ovulation and raise the risk, too
Obesity
Being overweight or obese can affect hormone levels. This can change the way the ovaries work.
References
- Evaluating infertility. The American Congress of Obstetricians and Gynecologists website. Available at: https://www.acog.org/womens-health/faqs/evaluating-infertility. Accessed November 17, 2021.
- Infertility in women. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/infertility-in-women. Accessed November 11, 2021.
- Overview of infertility. Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/gynecology-and-obstetrics/infertility/overview-of-infertility. Accessed November 17, 2021.
- Treating infertility. The American Congress of Obstetricians and Gynecologists website. Available at: https://www.acog.org/womens-health/faqs/treating-infertility. Accessed November 11, 2021.
Contributors
- Mary-Beth Seymour, RN
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