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Symptoms of Peptic Ulcer Disease

Authors:
  • Cynthia M. Johnson, MA
Publication Type:

Condition InDepth

Symptoms of Peptic Ulcer Disease

Some people do not have symptoms. In others, symptoms may come and go. Problems may be:

  • Burning stomach pain that:
    • May wake a person up from sleeping
    • May last a few minutes or many hours
    • Is worse on an empty stomach—but better after eating or drinking
    • Feels better after taking antacids
  • Nausea and vomiting
  • Lack of hunger
  • Burping
  • Bloating
  • Feeling of fullness
  • Heartburn

Ulcers can cause bleeding. It is rare but heavier bleeding can cause:

  • Bloody or black, tarry stools (poop)
  • Vomiting that looks like coffee grounds or blood

References

  • Lanas A, Chan FKL. Peptic ulcer disease. Lancet. 2017;390(10094):613-624.
  • Peptic ulcer disease. EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/peptic-ulcer-disease. Accessed May 4, 2022.
  • Peptic ulcer disease. Merck Manual Professional Version website. Available at: http://www.merckmanuals.com/professional/gastrointestinal-disorders/gastritis-and-peptic-ulcer-disease/peptic-ulcer-disease. Accessed May 4, 2022.
  • Peptic ulcers (stomach ulcers). National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: https://www.niddk.nih.gov/health-information/digestive-diseases/peptic-ulcers-stomach-ulcers/all-content. Accessed May 4, 2022.

Contributors

  • Daniel A. Ostrovsky, MD
Last Updated:
2022-02-04

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This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.