Other Treatments for Myelodysplastic Syndrome (MDS)
Peripheral Stem Cell Transplant
MDS and its treatment causes a drop in the number of healthy blood cells in the marrow. A peripheral stem cell transplant (PBSCT) uses healthy stem (unformed) cells from the blood of a donor. The stem cells travel to bone marrow sites all over the body. Slowly, they return the numbers of blood cells to a normal range. If PBSCT works, the new cancer free cells should make healthy new ones.
Types of PBSCT:
A PBSCT is not for everyone. Success rates vary depending on age, gender, and how aggressive MDS is. Side effects include rejection of the new cells and return of MDS. With rejection, the new blood cells are thought of as foreign and the body attacks them.
Central Venous Catheter
A soft, thin, flexible tube is placed in a large vein in the body. Common sites are under the collarbone or in the chest. These tubes eliminate the need for repeated needlesticks. The tube links to a different tube that is fixed to the outside of the body. The tube can be used to give medicine or take blood samples.
Tissue from the marrow is removed from the person with MDS. The donated marrow is given through a vein in the chest. Then, the person with MDS is kept away from others. This is to lower the risk of infection while blood cells are restored. It can take up to a month for this to happen.
- Myelodysplastic syndrome (MDS). EBSCO DynaMed website. Available at: https://www.dynamed.com/condition/myelodysplastic-syndrome-mds. Accessed April 20, 2022.
- Treating myelodysplastic syndromes. American Cancer Society website. Available at: https://www.cancer.org/cancer/myelodysplastic-syndrome/treating.html. Accessed April 20, 2022.
- Treatment option overview. National Cancer Institute website. Available at: https://www.cancer.gov/types/myeloproliferative/patient/myelodysplastic-treatment-pdq#section/_49. Accessed April 20, 2022.
- Mohei Abouzied, MD, FACP
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