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Chemotherapy for Testicular Cancer

  • Amy Scholten, MPH
Publication Type:

Condition InDepth

Chemotherapy for Testicular Cancer

Chemotherapy (chemo) uses drugs to kill testicular cancer cells. The drugs enter the bloodstream and travel through the body. It is mainly used after surgery, if cancer has spread beyond the testicles. It may also be used to ease symptoms from cancer that has spread. For nonseminomas, it may be used with radiation therapy.

Chemotherapy Drugs and Delivery

There are many types of chemo drugs. For testicular cancer, they work better when more than one is used. The type and mix of drugs will be based on the cancer type. It will also depend on how the person reacts to the drugs. The most common are:

  • Cisplatin
  • Bleomycin
  • Etoposide
  • Paclitaxel
  • Vinblastine
  • Ifosfamide

Chemo is most often given through an IV. But some come in pill form. They are given in cycles over a set time. The doctor will help find out how many cycles are needed and which drugs will work best.


  • Chemotherapy for testicular cancer. American Cancer Society website. Available at: https://www.cancer.org/cancer/testicular-cancer/treating/chemotherapy.html.
  • Drugs approved for testicular cancer. National Cancer Institute website. Available at: https://www.cancer.gov/about-cancer/treatment/drugs/testicular.
  • High-dose chemotherapy and stem cell transplant for testicular cancer. American Cancer Society website. Available at: https://www.cancer.org/cancer/testicular-cancer/treating/high-dose-chemo-stem-cell.html.
  • Management of nonseminoma testicular cancer. EBSCO DynaMed website. Available at: https://www.dynamed.com/management/management-of-nonseminoma-testicular-cancer.
  • Management of seminoma. EBSCO DynaMed website. Available at: https://www.dynamed.com/management/management-of-seminoma.


  • Mohei Abouzied, MD, FACP
Last Updated:

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.