PET Scan for Prostate Cancer
Procedure
(Prostate Specific Membrane Antigen Scan; PSMA Scan; Gallium 68 Scan; Choline C-11 Scan; Choline F-18 Scan)
Definition
PET scans use low-level radioactive material to show certain cells. Different types of radiation may be used. The radioactive material options for prostate cancer tissue include:
- Gallium 68
- Choline C-11 or F-18
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Reasons for Test
This scan will help find cancer cells. Cancer cells need a lot of energy. Cells that use a lot of energy will take in more radioactive material. This will make them easier to see on scan.
- Gallium 68 helps find cancer that has spread beyond the prostate. It may be used before treatment begins or to look for new areas after treatment.
- Choline C-11 or F-18 is used for those who have had prostate cancer treatment. The scan may be used if someone is at a high risk for cancer coming back.
Possible Complications
Problems are rare, but all procedures have some risk. Your doctor will go over some problems that could happen, such as:
- Changes in the levels of bilirubin (a waste product) in the blood
- Increase in liver enzymes
- Changes in blood pressure
- Allergic reaction to radioactive material
What to Expect
Problems To Look Out For
- Nausea
- Dizziness
- Diarrhea
If you think you have an emergency, call for medical help right away.
American Cancer Society
National Cancer Institute
CANADIAN RESOURCES:
Canadian Cancer Society
Health Canada
American Cancer Society
National Cancer Institute
CANADIAN RESOURCES:
Canadian Cancer Society
Health Canada
References
- Farolfi, A., Calderoni, L., et al. Current and emerging clinical applications of PSMA PET diagnostic imaging for prostate cancer. Journal of Nuclear Medicine, 2021; 62(5): 596-604.
- FDA approves first PSMA-targeted PET imaging drug for men with prostate cancer. U.S. Food and Drug Administration website. Available at: https://www.fda.gov/news-events/press-announcements/fda-approves-first-psma-targeted-pet-imaging-drug-men-prostate-cancer.
- Highlights of prescribing information. U.S. Food and Drug Administration website. Available at: https://www.accessdata.fda.gov/drugsatgda_docs/label/2012/203155s000lbl.pdf.
- Prostate cancer diagnosis and staging. EBSCO DynaMed website. Available at: https://www.dynamed.com/evaluation/prostate-cancer-diagnosis-and-staging.
- Prostate specific membrane antigen (PSMA) PET imaging for prostate cancer. UCSF Department of Radiology and Biomedical Imaging website. Available at: https://radiology.ucsf.edu/psma-pet-scan-for-prostate-cancer.
Contributors
- Nicole Meregian, PA
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